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Authors: William Clarke, PhD, Lori J. Sokoll, PhD Last modified: October 24, 2001
  • Although AFP can indicate the presence of cancer, it is important to note that it is not specific for one type of cancer and should not be used for general screening purposes in healthy patients
  • In general, higher concentrations of AFP correspond to larger tumors
  • AFP can be used in conjunction with human chorionic gonadotropin (hCG) for staging of germ-cell tumors
  1. Chan DW and Sell S ;  Tumor Markers ;  Burtis CA and Ashwood ER (eds.): Tietz Fundamentals of Clinical Chemistry, 5th ed., Ch. 21, Philadelphia, PA, WB Saunders, 2001.

  2. Wu JT ;  Diagnosis and Management of Cancer Using Serologic Tumor Markers. ;  Henry JB (ed.): Clinical Diagnosis and Management by Laboratory Methods, 20th ed., Ch. 47, Philadelphia, PA, WB Saunders, 2001.

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